Using a zebrafish model, Wayne and her colleagues found that exposure to low levels of BPA and BPS — equivalent to the traces found in polluted river waters — altered the animals’ physiology at the embryonic stage in as quickly as 25 hours.<\/em><\/p>\n“Our study shows that making plastic products with BPA alternatives does not necessarily leave them safer,” stated senior author Nancy Wayne, a reproductive endocrinologist and a professor of physiology at the David Geffen School of Medicine at UCLA<\/p>\n
“Egg hatching time accelerated, leading to the fish equivalent of premature birth. The embryos developed much faster than normal in the presence of BPA or BPS.”<\/p>\n
“Exposure to low levels of BPA had a significant impact on the embryos’ development of brain cells that control reproduction, and the genes that control reproduction later in life. We saw many of these same effects with BPS found in BPA-free products. BPS is not harmless.”<\/p>\n
Using fluorescent-green protein tags, the researchers tracked the fishes’ development of reproductive endocrine brain cells, which control puberty and fertility. In a second finding, the team discovered that the number of endocrine neurons increased up to 40 percent, suggesting that BPA overstimulates the reproductive system.<\/em><\/p>\nWayne suspects that overstimulation of the neurons that regulate reproduction could lead to premature puberty and disruption of the reproductive system. Her lab plans to investigate this question in a future study.<\/em><\/p>\n“Our findings are frightening and important,” continued Wayne. “Consider it the aquatic version of the canary in the coal mine.”<\/p>\n
“Most people think of BPA as mimicking the effects of estrogen. But our work shows that it also mimics the actions of thyroid hormone. Because of thyroid hormone’s important influence on brain development during gestation, our work holds important implications for general embryonic and fetal development, including in humans.”<\/p>\n
As premature births have been on the rise in the US (and elsewhere) over the last few decades, the findings are worth taking note of.<\/p>\n
“If BPA is impacting a wide variety of animal species, then it’s likely to be affecting human health. Our study is the latest to help show this with BPA and now with BPS.”<\/p>\n
“BPA can leach into food, particularly under heat, from the lining of cans and from consumer products such as water bottles, baby bottles, food-storage containers and plastic tableware. BPA can also be found in contact lenses, eyeglass lenses, compact discs, water-supply pipes, some cash register and ATM receipts, as well as in some dental sealants and composites. The US and Europe were expected to manufacture more than 5 million tons of products containing the additives in 2015.”<\/p>\n","protected":false},"excerpt":{"rendered":"
In a finding that should surprise exactly no one with any critical faculties remaining, it turns out that the replacement for BPA used in “BPA-free” plastic — BPS (Bisphenol S) — is itself involved in reproductive system disruption and altered embryonic development. The new finding (which has been expected by anyone who have been paying 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