Washington, D.C. — The compound sulforaphane whose natural precursors are found at high levels in broccoli and other cruciferous vegetables has been hailed for its chemopreventive powers against cancer. Now sulforaphane has demonstrated new skills in treating a genetic skin blistering disorder called epidermolysis bullosa simplex (EBS), Pierre Coulombe and colleagues at the Johns Hopkins University School of Medicine in Baltimore report at the American Society for Cell Biology 47th Annual Meeting.
EBS is a rare but devastating inherited condition in which fluid-filled lesions called bullae appear at sites of frictional trauma to the skin. Unfortunately, treatment options for EBS are limited and palliative in nature. Much work remains to be done before sulforaphane can be tested clinically with EBS patients, but Coulombe notes that extracts from broccoli sprouts rich in sulforaphane have already been shown to be safe for use in human skin.
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Noelle dEstries
Noelle d'Estries, an early GO employee who took on the varied roles of Community Manager, green celebrity blogger, and more. She currently runs worstcookever.com GO entered Noelle's life in February 2007 while she was burning tires in her backyard. A phone call from the green gods at GO, burnt out the fires. Now, Noelle happily wears her GO sweatshirt while eating organic veggies and asking for paper, not plastic. A regular at the local farmer's market, Noelle shuns raking leaves and lawn maintenance, while making gourmet foods constantly. When not staring at her computer screen, she spends time with her equally attractive dog, Tessa, cat, Tim and lover Paul. She currently holds all three point records at RIT and could eat avocados and drink wine for the rest of her life.
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