CLEVELAND—How can some people live at high altitudes and thrive while others struggle to obtain enough oxygen to function?
The answer for Tibetans who live at altitudes around 14,000 feet is increased nitric oxide (NO) levels. High levels of NO circulate in various forms in the blood and produce the physiological mechanisms that cause the increased blood flow that maintains oxygen delivery despite hypoxia—low levels of oxygen in the ambient air and the bloodstream. Researchers from Case Western Reserve University and the Cleveland Clinic report that Tibetans have 10 times more NO and have more than double the forearm blood flow of low-altitude dwellers. The findings from a comparison of NO levels in the high and low altitude dwellers are reported in the article, “Higher Blood Flow and Circulating NO Products Offset High-altitude Hypoxia among Tibetans,” in the current Proceedings of the National Academy of Sciences (PNAS).
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Noelle dEstries
Noelle d'Estries, an early GO employee who took on the varied roles of Community Manager, green celebrity blogger, and more. She currently runs worstcookever.com GO entered Noelle's life in February 2007 while she was burning tires in her backyard. A phone call from the green gods at GO, burnt out the fires. Now, Noelle happily wears her GO sweatshirt while eating organic veggies and asking for paper, not plastic. A regular at the local farmer's market, Noelle shuns raking leaves and lawn maintenance, while making gourmet foods constantly. When not staring at her computer screen, she spends time with her equally attractive dog, Tessa, cat, Tim and lover Paul. She currently holds all three point records at RIT and could eat avocados and drink wine for the rest of her life.
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